House Grail is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

10 Best Tile Floor Cleaners for Dog Urine in 2022 – Reviews & Top Picks

grout and tiles cleaning

grout and tiles cleaning

Part of the reason you opt for tile is cleanability and durability, so it may not seem like a huge deal when your puppy has a random accident in the kitchen. But dog pee stench is persistent, and even the most aggressive solutions won’t keep the smell away for long. In many cases, chemical cleaners can do more harm than good, not only failing to eliminate the dog urine odor but also damaging your tile and grout.

With some basic understanding of what works to clean pet pee, you can skip the abrasive cleaners and jump straight to safe yet effective solutions for even the most intense dog stains on the kitchen or bathroom floor. Save yourself time and frustration the next time your dog takes a poorly timed bathroom break by checking out these reviews on the ten best tile floor cleaners for dog urine.

divider 5

A Quick Comparison of our Favorites in 2022

Rating Image Product Details
Best Overall
Winner
Shop Care Super Enzyme Pet Urine & Odor Destroyer Shop Care Super Enzyme Pet Urine & Odor Destroyer
  • Fast-acting
  • Light, pleasant fragrance
  • Useful for a variety of indoor and outdoor surfaces
  • Best Value
    Second place
    Ion Fusion Severe Pet Urine & Odor Destroyer Ion Fusion Severe Pet Urine & Odor Destroyer
  • Biodegradable, non-toxic
  • Pleasant blueberry scent
  • Recharge pack included
  • Premium Choice
    Third place
    Urine Off Dog & Puppy Formula Urine Off Dog & Puppy Formula
  • Powerful, targeted bio-enzymatic formula
  • Appropriate for a variety of soft and hard surfaces
  • Eco-friendly
  • Urine Off Dog & Puppy Formula Urine Off Dog & Puppy Formula
  • Mild fragrance
  • Useful for several organic stains
  • Effective on a variety of hard and soft surfaces
  • Simple Solution Pet Urine Destroyer Simple Solution Pet Urine Destroyer
  • Safe to use on a variety of materials
  • Great for cat and dog urine
  • Prevents remarking
  • The 10 Best Tile Floor Cleaners for Dog Urine

    1. Shop Care Super Enzyme Pet Urine & Odor Destroyer – Best Overall

    Shop Care Super Enzyme Pet Urine & Odor Destroyer

    Cleaner type Bio-enzymatic
    Dwell time 5 minutes

    From a glance at the packaging, Shop Care’s Super Enzyme Pet Urine & Odor Destroyer has the look of an industrial-strength cleaner. Once you start using it, you’ll notice it has the power of one as well.

    The Super Enzyme solution is an excellent value at its mid-tier price point. Shop Care proudly recommends its use for professional applications, including veterinarians’ offices, grooming salons, and kennels.

    Thanks to its powerful enzyme blend, this cleaner is eco-friendly, effective, and safe for nearly any surface. Take it outside to treat turf and gravel, or use it inside on tile, carpet, vinyl, and more. Whether your dog just had an accident or you have a days-old stain, Shop Care’s enzyme cleaner will break down and lift dog pee on tile and grout safely and effectively.

    Pros
    • Useful for a variety of indoor and outdoor surfaces
    • Fast-acting
    • Light, pleasant fragrance
    Cons
    • No spray nozzle
    • May need additional treatments to prevent re-marking

    2. Ion Fusion Severe Pet Urine & Odor Destroyer – Best Value

    Ion Fusion Severe Pet Urine & Odor Destroyer

    Cleaner type Charged ion surfactant and deodorizer
    Dwell time None

    ION Fusion’s Severe Pet Urine & Odor Destroyer is one of the more offbeat solutions for dog urine stains, taking a unique approach to both the formula and the packaging, and is the best tile cleaner for dog urine for the money. Instead of using enzymes, this spray uses plant-based ions, solvents, and deodorizers to lift all kinds of stains, including urine, blood, feces, dirt, food, and grease. With non-toxic ingredients presenting zero VOCs or harsh fumes, the naturally derived cleaner follows ION Fusion’s commitment to the environment.

    It’s a clever, versatile, and eco-friendly solution, but what makes ION Fusion’s product the best tile floor cleaner for the money is the sprayer. The ergonomic sprayer makes it easy to spray in any position and ensures that you use every last drop. When it finally runs dry, pop the included refill cartridge into the sprayer, add water, and you have a brand new 32 ounces of cleaner to use on future stains!

    Pros
    • Useful for numerous organic stains
    • Ergonomic bottle uses every bit of cleaner
    • Recharge pack included
    • Biodegradable, non-toxic
    • Pleasant blueberry scent
    Cons
    • May not be effective on old stains

    3. Urine Off Dog & Puppy Formula – Premium Choice

    Urine Off Odor and Stain Remover Dog Formula

    Cleaner type Bio-enzymatic
    Dwell time 2–5 minutes; overnight for old stains

    The bio-enzymatic formula in Urine Off’s Dog & Puppy Formula specifically targets urine, making it potentially the most practical dog pee cleaner on this list. Helpful bacteria release enzymes that break down uric acid and urine proteins, allowing the bacteria to digest and remove the waste as harmless byproducts. Containing high-quality ingredients and few chemicals, this environmentally friendly USDA-certified biobased cleaner is safe to use around family and pets.

    Urine Off is powerful enough to get out the toughest pee stains on carpeting, and it’s even more potent on hard surfaces, including hardwood and tile. Spray it on the tile, scrub for a few seconds for tough stains, and let it sit to release set-in urine. You may have to let it work for several hours for old spots that dig into unsealed grout, but you can count on it to get the job done.

    Pros
    • Powerful, targeted bio-enzymatic formula
    • Appropriate for a variety of soft and hard surfaces
    • Eco-friendly and safe to use around people and pets
    Cons
    • More expensive than other enzyme cleaners
    • Cleaner odor can be irritating

    Are you looking for an enzyme cleaner that can keep your house clean and your pet happy? We recommend the Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray, which permanently gets rid of the most stubborn stains and smells. There’s even a 100% satisfaction guarantee so you can try this cleaner risk-free! Click here to order your first bottle.

    At House Grail, we’ve admired Hepper for many years, and decided to take a controlling ownership interest so that we could benefit from the outstanding products of this cool cat company!


    4. ECOS for Pets! Stain & Odor Remover

    EARTH FRIENDLY Ecos, Odor Remover Pet

    Cleaner type Enzymatic
    Dwell time 5 minutes

    If we had to rework this list, the stain and odor remover spray from ECOS could easily take the top spot. It’s an excellent value at its price point, and it gets rave reviews, with customers loving its overall effectiveness and mild scent.

    The ECOS formula is a general enzyme cleaner, meaning it’s great to have on hand for an array of organic stains, including people and pet urine, vomit, and blood. The plant-derived cleaning agents are color-safe and non-toxic for humans and animals, so you can feel good about using the spray on any surface. For fans of green cleaning, this multi-surface eco-friendly cleaner is a must-have.

    Pros
    • Effective on a variety of hard and soft surfaces
    • Useful for several organic stains
    • Mild fragrance
    • Eco-friendly and safe around people and pets
    Cons
    • May be ineffective on deep, set-in spots

    5. Simple Solution Pet Urine Destroyer

    Simple Solution Pet Urine Destroyer

    Cleaner type Bio-enzymatic
    Dwell time 10 minutes; 24–48 hours to dry

    If you have cats and dogs in the house and pee stains are a frequent concern, Simple Solution’s Pet Urine Destroyer could be the perfect fit for your needs. The bio-enzymatic formula uses targeted bacteria for tough urine stains. Except for wool and leather, you can use this on any water-safe indoor or outdoor surface to combat residue and odors, no matter how long the stain has been there.

    Unlike many other options, Simple Solution uses a flip-top sprayer to apply the cleaner. Saturate the stain, let it sit for a few minutes, and blot it up. Use the solution on everything from your tile floor to a laundry pre-treatment to get any trace of stains and odor out for good.

    Pros
    • Safe to use on a variety of materials
    • Great for cat and dog urine
    • Prevents remarking
    Cons
    • Initial smell can be irritating
    • Can take 24–48 hours to dry

    6. OUT! PetCare Advanced Stain & Odor Remover

    OUT! Advanced Stain and Odor Remover

    Cleaner type Bio-enzymatic
    Dwell time 5 minutes; 24–48 hours to dry

    OUT! markets the PetCare Advanced product for carpet and upholstery, but it’s appropriate for any water-safe surface, including tile. It makes our list because the bio-enzymatic solution is not only practical, but with the 2-bottle offer, you get an incredible deal on a versatile dog pee cleaner for tile, carpets, and more.

    The PetCare Advanced cleaner leans on its 3X pro-bacteria and enzyme formula to power out tough urine stains and odors. Along with urine, you can use it to clean up most organic messes, including blood, grass, and feces. The bottle itself is also a benefit, offering three ways to apply the cleaner—mist, foam, or stream—so you can get the best results and most convenience for any unique situation.

    Pros
    • Powerful pro-bacteria enzyme solution
    • Suitable for a variety of surfaces
    • Handles several types of organic stains
    • Prevents remarking
    • Three ways to apply the cleaner
    Cons
    • Not usable on leather or wool
    • Can take 24–48 hours to dry

    7. TriNova Pet Stain & Odor Remover

    TriNova Natural Pet Stain and Odor Remover Eliminator

    Cleaner type Bio-enzymatic
    Dwell time 3–5 minutes

    Take one look at the earth-colored bottle, and you’ll see that TriNova took the green cleaning route with their stain and odor remover spray. Simple ingredients such as bacteria, digestive enzymes, bamboo extract, and mint essential oils combine to make a powerful yet non-toxic, organic solution for urine, vomit, feces, and more.

    TriNova’s Pet Stain & Odor Remover is a pricey option, but you get what you pay for here. It’s safe, versatile, fast-acting, and, in many cases—permanent. If you have an issue with your dog marking on tile surfaces, this bacteria-based formula will destroy the odor, lift the stain and any residue, and make it seem like it never happened.

    Pros
    • Powerful bio-enzyme formula
    • Useful for a variety of hard and soft surfaces
    • Fights several types of tough organic stains
    • All-natural ingredients
    Cons
    • Expensive

    8. Nature’s Miracle Dog Stain & Odor Remover

    Nature's Miracle Stain & Odor Remover Trigger Spray

    Cleaner type Bio-enzymatic
    Dwell time 10 minutes

    Nature’s Miracle is committed to combating pet odors no matter where they show up, offering everything from spray cleaners and shampoos to kitty litter and poop scoopers. With its Dog Stain & Odor Remover, you get a quintessential enzyme cleaner from the quintessential cleaning brand. Although you can also purchase a hard surface cleaner for even more targeted cleaning, this multi-surface cleaner makes our list because it’s more versatile and equally effective no matter where your puppy does their business.

    The Dog Stain & Odor Remover formula uses bacteria and enzymes to remove dog pee. Spray the stain, wait 10 minutes, and then blot it up. Lingering enzymes continue breaking down any particles they come across, leaving you nothing but a light citrus scent to replace that dog urine stench.

    Pros
    • Useful for several hard and soft surfaces
    • Works on a variety of pet stains
    • Continues working after cleaning
    Cons
    • Odor can be overpowering
    • Needs 24 hours to dry

    9. Rocco & Roxie Professional Strength Pet Stain & Odor Eliminator

    Rocco & Roxie Stain & Odor Eliminator

    Cleaner type Bio-enzymatic
    Dwell time 5–10 minutes

    Rocco & Roxie’s bio-enzymatic Professional Strength Pet Stain & Odor Eliminator gets top marks in nearly every category, from its scent to its effectiveness on tough stains. If it wasn’t more expensive than the other listed options, this product would likely earn the top spot. It works on all kinds of organic pet messes beyond urine, and it’s safe for virtually any hard or soft surface.

    The professional strength formula is as effective as any cleaner on new or old urine stains, but it avoids many of the common pitfalls you’ll see from other brands. The initial scent is subtle and pleasant, and on tough urine stains, you don’t have to wait up to 24 hours before vacuuming. For dog pee marks on tile, you can often clean it up in minutes, but at worst, you may have to let it soak for an hour before drying.

    Pros
    • Powerful enzymatic formula for tough stains
    • Works on a variety of organic pet messes
    • Suitable for numerous soft and hard surfaces
    • Pleasant scent
    Cons
    • Expensive
    • May leave a greasy residue

    10. Simple Solution Stain & Odor Remover

    Simple Solution Pet Stain and Odor Remover

    Cleaner type Enzymatic
    Dwell time 10+ minutes; 24–48 hours to dry

    Get back to basics with Simple Solution’s Stain & Odor Remover, a general enzyme cleaner for dog and cat messes wherever they show up. Use it from carpet to tile for anything your dog doles out, whether it’s urine, feces, vomit, or drool.

    Simple Solution isn’t exciting for any specific reason compared to other enzyme cleaners. But given its versatility, it represents fantastic value. The bottle, however, is a nice touch. Like the spray from OUT!, this one comes with a convertible head, letting you switch between mist, stream, and foam for extra adaptability.

    Pros
    • Versatile across hard and soft surfaces
    • Useful for various organic pet messes
    • Three ways to apply the cleaner
    Cons
    • Requires a heavy application for tough stains
    • May leave an unpleasant aroma
    • Can take 24–48 hours to dry

    divider 5

    Buyer’s Guide – Choosing the Best Tile Cleaner for Dog Urine

    What is the Best Tile Floor Cleaner for Dog Urine?

    Shop Care’s Super Enzyme Pet Urine & Odor Destroyer is the best tile floor cleaner for dog urine primarily because of its concentrated enzyme formula. Many other cleaners made it on this list for the same reason, as enzyme cleaners are the most effective for pee stains across most surfaces.

    Unlike steam, bleach, all-purpose cleaner, and many other cleaning alternatives that are ineffective or even counterproductive to use on old pee stains, bio-enzyme cleaners break down the stubborn, stuck-on uric acid crystals that create those long-lasting smells. They remove the spot and the stink rather than masking them, keeping the smell from coming back or encouraging repeat offenses.

    For tile and most surfaces in general, the best way to dry enzyme cleaners is to use a shop vac. Paper towels will soak up most of the remaining liquid, but a high-powered vacuum will extract moisture deep within porous unsealed grout or tile.

    dog pee on wooden vinyl hardwood floor
    Image Credit: New Africa, Shutterstock

    Can Dog Urine Cleaner Damage Tile Floors?

    Many people opt for DIY cleaners for immediate dog accidents, using baking soda and vinegar as a go-to homemade solution. While this is often ineffective on older stains, the bigger problem with using vinegar is that acidic ingredients eat through cement-based grout if it’s unsealed. Over time, that could lead to grout and tile deterioration, moisture penetration, and potentially subfloor problems.

    Unless your tile floor is sealed or uses epoxy or urethane grout, you need to avoid acidic cleaners like vinegar. Fortunately, the most effective solutions—enzyme cleaners—are usually safe on both sealed and unsealed grout. Before using any cleaner, always check the instructions to ensure your surface is safe.

    Related Read: 10 Best Cleaners for Dog Urine on Laminate Floors: Reviews & Top Picks

    divider 5

    Final Thoughts

    Our dogs bring boundless joy into our lives, and the occasional pee stain is a small price to pay for their company. Still, in those random moments where they forget themselves, having an effective cleaner at the ready can make all the difference in clearing the air and avoiding the headache of repeat messes.

    While we recommend you try any of these ten best tile floor cleaners for dog urine the next time your four-legged pal has an accident in the kitchen, Shop Care’s Super Enzyme Pet Urine & Odor Destroyer is our favorite, and you’ll have no trouble getting rid of the stink once and for all! For a more budget-friendly option, ION Fusion’s Severe Pet Urine & Odor Destroyer is the best choice for the money.


    Featured Image Credit: Odua Images, Shutterstock

    Related posts

    OUR categories

    Project ideas

    Hand & power tools

    woodworking

    Garden

    Automotive