11 Best Cleaners for Dog Urine on Laminate Floors in 2025 – Reviews & Top Picks

Do you have an ultra-excited puppy doing the puppy dance, or maybe old faithful’s bladder isn’t quite what it used to be? Even the best-trained dogs can have an accident. If it only happens once and you’re able to clean it up right away, you’re probably in the clear. However, if it becomes a regular occurrence, you’re going to need something to clean up that laminate floor.

There are a lot of cleaners on the market, and the choices can certainly become overwhelming. So, done the heavy lifting for you and found and reviewed ten of the best cleaners for dog urine on laminate floors available right now!

A Quick Comparison of Our Favorites for 2025

The 11 Best Cleaners for Dog Urine on Laminate Floors

1. Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray – Best Overall

The best overall cleaner for dog urine on laminate floors is the Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray. This product stands out because it is convenient, safe for many floor types, and penetrates to remove smells, stains, and all dog messes.

The Hepper product utilizes bio-enzymes that bind, lift, and remove urine stains and odors directly from the floor. The product is even strong enough for other messes, including feces or vomit. Plus, these enzymes actually remove odors to prevent dogs from urinating in the same spot again.

All the while, this product is more convenient than other competitors. It does not require any mixing, and it comes in a big bottle so that you do not have to worry about running out. Simply shake the bottle and spray away the messes for quick, convenient, and efficient clean-up.
Whether you’re dealing with recent messes or long-lasting odors, the Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray is the product for you.

At House Grail, we’ve admired Hepper for many years and decided to take a controlling ownership interest so that we could benefit from the outstanding designs that look great in every home!

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2. Nature’s Miracle Dog Set-In Stain Destroyer Oxy Formula – Best Value

Suppose you’re not looking for the absolute best available but looking to find the best cleaner for the money. In that case, Nature’s Miracle Stain Destroyer is one to consider. Its oxygen-based formula works hard to lift even the most stubborn stains. You might be tempted to use this as your regular floor cleaner too. Because not only does it clean great, but it leaves behind a refreshing orange scent.

Another benefit that contributes to it taking the best for the money title is that it is safe to use around your dog. So, there’s no need to keep them out of the house until chemicals dissipate or anything like that.

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3. Simple Solution Pet Urine Destroyer – Premium Choice

Our premium choice is the Pet Urine Destroyer from Simple Solution. Not only is it reasonably priced for what you get, but an overwhelming number of people who use it rate it highly. It’s formulated with special enzymes that work on the toughest stains your furry friends might leave behind. Because it eliminates the urine at the source, it helps prevent repeat future accidents. It’s conveniently available in a 32oz bottle or one-gallon jugs, depending on how much cleaning you need to get done.

One of the main factors that give it such an excellent rating is its versatility. Not only will it work wonders on your laminate floor, but it’s suitable for any water-safe surface in your home.

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4. Nature’s Miracle Dog Urine Destroyer Foam

One usually associates a spray bottle or mop and bucket when it comes to cleaning up pet messes. Nature’s Miracle gives us a terrific urine cleaner that you can use just about anywhere or on anything in your house in the form of an aerosol can. Like many others in this list, it has an enzyme formula that breaks down urine at its source to help discourage future accidents.

As long as you follow the directions, this cleaner is also safe to use around your furry friends. And its reasonable price tag makes this one a strong contender on the list.

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5. MisterMax Anti-Icky-Poo

While it may have a somewhat silly name, Anti-Icky-Poo means business. This highly-rated cleaner is available in a scented or unscented version, and it’s designed to clean all your dog’s messes on any of the hard surfaces in your home. Even the unscented version is a deodorizer. So, instead of getting a cleaner that kind of gets the job done but masks it with a pleasant scent—there’s no scent to mask the odor, so you KNOW it’s working!

Oh, and in case you’re wondering, this one is made with safe ingredients for your pets as well, so no worries about them being around when you’re cleaning.

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6. Simple Solution Extreme Stain & Odor Remover

If there is one thing that Simple Solution does well, it is stain and odor removal, hence it getting multiple spots on our list. This particular one is not only is it reasonably priced for the product you’re getting, it’s actually a professional-quality cleaning formula. It’s formulated to remove the toughest stains your four-legged family members can throw at it. It’s also designed to help discourage repeat accidents if your pup thinks they’ve found their new bathroom spot.

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7. Rocco & Roxie Supply Co. Professional Strength Pet Stain & Odor Eliminator

This cleaner from Rocco & Roxie really stands apart for its versatility. It does an incredible job of eliminating stains and odors, but it has a pleasant scent that can be used as a deodorizer to freshen up all the places your pets spend a lot of time, such as the car, their beds, crates, or litters boxes. If that wasn’t enough to get you excited about this one, the fact that it is a professional grade cleaner that is actually approved by the Carpet and Rug Institute should tell you what you need to know.

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8. Stink Free Hardfloor Pet Stain & Odor Remover

Stink Free’s cleaner is an excellent choice for your home’s hard surfaces, such as your laminate flooring. It’s as simple as sweeping the floor, spraying a generous amount of the cleaner on stained or smelly areas, and wiping it up. It’s made with non-toxic materials, so it’s safe to use around your pets or kids without the need to rinse with fresh water afterward, like some products. It is a professional grade cleaner, but it has some usage limitations. For example, it will damage a wax finished floor.

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9. KIDS ‘N’ PETS – Instant All-Purpose Stain & Odor Remover

Jack of all trades, master of none, may not be an accurate way to describe this all-purpose cleaner because it does a pretty darn good job, according to reviews. The best part of this one is that it’s not limited to just working on dog urine. It will work on all the stains and smells that come along with having a household of pets and kids. Plus, it works on just about any surface you can imagine—including clothes as a pre-wash treatment. Like any other cleaner, you’re going to want to do a colorfast test before cleaning cloth or material, but it’s ideal for a laminate floor.

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10. Resolve Urine Destroyer Spray Stain & Odor Remover

Resolve is a brand that is well known for its cleaning products, especially carpet cleaning. However, this particular spray cleaner has urine-destroying technology that neutralizes the odor at the source, thus helping to prevent reoccurring accidents. Even though it’s an aggressive cleaner, it is still safe to use around your kids—human and the four-legged variety! You can use it on many different surfaces, but this one is really only meant to be a spot cleaner—which shouldn’t be a problem for most laminate floor cleanups.

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11. Nature’s Miracle Hard Floor Cleaner

Last but not least, we have another cleaner by Nature’s Miracle. This cleaner is specifically formulated to work on hard surfaces like tile or laminate floors. It works well on hardwood floors too. This bio-enzymatic cleaner works to trap odors and eliminate them to help prevent Fido from choosing the same spot on your floor the next time he’s got to go. Another nice thing about this particular cleaner is that you don’t have to rinse; just spray and wipe.

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Buyer’s Guide – How to Choose the Best Cleaner for Dog Urine on Laminate Floors

As you can see by this list, many cleaners are similar; though, they are certainly not all equal. Some are proven to be more effective than others, and some are safer. One of the main factors you should consider, though, is what type of surface you’re cleaning.

By reading this list, you obviously have laminate flooring or another hard floor. But will you potentially have to clean carpet or other fabric in the future? These are things to consider because you can potentially purchase one cleaner that will take care of all your needs.

Another thing to consider is the size. For example, many of the cleaners on this list are available in multiple sizes. And often, there is more value in buying a cleaner in a one-gallon jug and then mixing it in a smaller spray bottle if it’s a concentrate.

It’s also worth noting that some cleaners are specifically designed for one type of animal. So, their enzymes are formulated specifically to react to dog urine, for example. If you have multiple pets, it’s probably worth searching for a more ‘universal’ or multipurpose urine cleaner.

• See Also: 10 Best Cleaners for Dog Urine on Hardwood Floors

Closing Thoughts

Based on our research, the best overall cleaner for laminate floors is Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray. It offers a great combination of extreme power while remaining more affordable than many on the list. On the other hand, Nature’s Miracle cleaner provides the best value if you’re looking for a great all-around urine cleaner compared to its inexpensive price tag.

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Featured Image Credit: MCarper, Shutterstock